Category Archives: Materials

Magnetic Beads Strip Blood Samples to Allow Circulating Tumor Cell Isolation

Researchers at the University of Georgia have developed a microfluidic chip to isolate circulating tumor cells (CTCs) from blood samples. Unlike other devices, this new chip uses magnetic microbeads to strip all the cells from the blood, leaving only the CTCs, in a technique the researchers have called “integrated ferrohydrodynamic cell separation”. The device is … Continue reading

Scientists Figure Out How to 3D Print Vascular Networks for Printed Organs

The field of tissue engineering has seen a lot of progress, with complex 3D systems being developed that offer strength, contain multiple cell types, and that can even perform a biological function. All this is child’s play if there is no viable vascular network to supply the nutrients to all the cells and to route … Continue reading

Electronic Wound Monitoring Bandage Tracks Lactate, Oxygen Levels

Healing large and complex wounds requires vigilant monitoring and frequent dressing changes. This generally means pain, might require general anesthesia, and can even be emotionally disturbing to patients. A less invasive method of wound monitoring, that lets the wounds remain undisturbed, is badly needed. As wounds heal, the chemical composition of their environment changes. A … Continue reading

Bioengineered Gel to Reduce Risk of Bone Marrow Transplants

Bone marrow transplantation is a potentially life-saving treatment for leukemia, multiple myeloma, and HIV. The procedure involves depleting the patient’s immune system, then infusing blood stem cells from a donor, which develop into a new immune system. Unfortunately, during the transplant process, patients are susceptible to disease and infection, making it risky and not recommended … Continue reading

Handheld Skin Bioprinter Heals Deep Open Wounds With Patient’s Own Cells

The human organism has a number of physiologic processes that work together to heal skin wounds. Sometimes wounds are so large and difficult that these healing mechanisms simply can’t access damaged tissues. Researchers at Wake Forest Institute for Regenerative Medicine in North Carolina are now reporting the development of a bioprinter that uses a patient’s own … Continue reading

Soft Robotic Micromachines Mechanically Stimulate Small Tissue Samples

Researchers at Ecole polytechnique fédérale de Lausanne in Switzerland have developed miniature soft robots that can mechanically stimulate tiny tissue samples when activated by near-infrared light. The tiny machines could act as medical implants with a role in on-demand drug delivery or to mechanically manipulate tissues. Other applications include medical research, as components of lab-on-a-chip … Continue reading

3D-Printed Sugar-Based Stent to Aid Vascular Surgery

Researchers at the University of Nebraska-Lincoln have developed a 3D-printed stent that can aid surgeons in stitching small arteries together. The small tube sits between the open ends of the artery and helps to hold them in place during stitching. The device is 3D-printed using a sugar-based material, meaning that it dissolves and disappears within … Continue reading

Smart Tattoos to Detect Fever, Sun Exposure, and Maybe Diagnose Diseases

Tattoos have a long history on the human skin, underlined by a find of a body in the Alps more than 5,000 years old that had tattoos all over it. While tattoos have mostly served as decorations, status symbols, and as parts of rituals, researchers at University of Colorado Boulder believe they can be made … Continue reading

Microchip for Growing and Studying 3D Brain Mimics

Over the past few years, neuroscientists have been able to grow ever larger and more complex spheroid cultures and organoids that replicate the structure and functionality of brain tissue. While these models are significantly better at mimicking parts of the brain compared to 2D cultures, they are much more challenging to study because it’s hard … Continue reading

Microscopic Implantable Sensors Measure Dopamine in Brain

Dopamine is a neural signaling molecule seemingly involved in nearly every aspect of the brain’s activity. Yet, there hasn’t been a practical way to monitor the long term levels of dopamine in lab animals, let alone in humans. The main problem is that sensors developed so far degrade in the brain within a matter of … Continue reading